Describe the Chemical Composition of Bone

Bone rigid body tissue consisting of cells embedded in an abundant hard intercellular material. Apatites are a crystalline form having the general formula Ca10 Po46 X2 and the most widely distributed type is hydroxy apatite HA where x is OH iii.

Bone Chemical Composition And Physical Properties Britannica

The nonliving intercellular material of bone consists of an organic component called collagen a fibrous protein arranged in long strands or bundles similar in structure and organization to the collagen of ligaments tendons and skin with small amounts of proteinpolysaccharides glycoaminoglycans formerly known as mucopolysaccharides chemically bound to protein.

. SubjectsGetty Images Living bone contains about 10 to 20 percent water and 60 to 70 percent bone mineral as explained by the University of Cambridge. Compact bone consists of closely packed osteons or haversian systems. Mature lamellar bone has the same chemical composition and material properties throughout the skeleton regardless of its mechanism of formationintramembranous or endochondralor its structural organizationcortical compact or trabecular bone.

The following describe the inorganic chemical composition of bone except. In vivo bone living bone in the body contains between 10 and 20 water. Bones are composed of two types of tissue.

Inorganic substances are represented by compounds of calcium phosphorus magnesium and other elements. Bone Deposit- Osteoblasts injured or when added strength is needed requires a diet rich in protein. Bone tissue thanks to the composition of the inorganic fraction of its matrix is the main reservoir of ions such as calcium almost 99 phosphorus 85 sodium and magnesium between 40 and 60.

The collagen provides a scaffolding surface for inorganic salt crystals to adhere see Figure 634a. The structure of the CaP solid phase in bone was first identified by deJong in 1926 as a crystalline calcium phosphate similar to geological apatite by chemical analyses and most importantly by X-ray diffraction 1. The osteon consists of a central canal called the osteonic haversian canal which is surrounded by concentric rings lamellae of matrix.

Cartilage and bone extracellular matrix The extracellular matrix ECM is a complex of self assembled macromolecules. Vitamins C D and A. Composition of bone 13 organic Collagen fiber matrix 88 organized around lamellae Non-collagen 12.

Between the rings of matrix the bone cells osteocytes are located in spaces called lacunae. ECM is not only a scaffold for the cells. Of its dry mass approximately 60-70 is bone mineral.

Science Picture CoCollection Mix. By mass osseous tissue matrix consists of 13rd collagen fibers and 23rds calcium phosphate salt. The organic components include osteoid and bone cells.

The inorganic components are mineral salts. Bone os has a complex structure and chemical composition. The two principal components of this material collagen and calcium phosphate distinguish bone from such other hard tissues as chitin enamel and shell.

Bone tissue makes up the individual bones of the human skeletal system and the skeletons of other vertebrates. Neonatal bone had lower levels of mineral and calcium and higher levels of organic material and sialic acid than adult bone suggesting increased glycoprotein content in neonatal bone. The X-ray diffraction data was confirmed a few years later 2.

Bone matrix is 90 to 95 composed of elastic collagen fibers also known as ossein and the remainder is ground substance. A hard outer layer that is dense strong and durable. Which form crystals around and between the collagen fibers of the organic fraction.

The matrix is hardened by the binding of inorganic mineral salt calcium phosphate in a chemical arrangement known as calcium hydroxylapatite. In a living organism up to 50 of water 2815 of organic and 2185 of inorganic substances are present in the bone of an adult person. It makes up around 80 percent of adult bone mass.

Most of the rest is collagen but bone also contains a small amount of other substances such as proteins and inorganic salts. The protein hexose sialic acid and uronic acid contents of the matrix were determined. It serves also as a reservoir for growth factors and cytokines and modulates.

And manganese Osteoblasts produce bone matrix called osteoids. Skeletal growth and development begin in utero and continue for nearly 2 decades in a series of. Hydroxyapatites or mineral salts Eighty-five percent of bone by mass Mainly calcium phosphates Responsible for bone hardness and its resistance to compression.

The bone tissue is made up of several types of bone cells such as osteoblasts and osteoclasts. When both types of components exist in proper amounts bones are very strong and durable but are not brittle. Glycoproteins proteoglycans lipids etc 13 inorganic mineral Mostly dense calcium phosphate in the form of highly insoluble crystals of hydroxyapatite 13 water Cells osteoblasts osteoclasts osteocytes bone lining cells.

The main constituent is the crystalline form of calcium phosphate known as apatite with some amorphous calcium phosphate except probably in enamel 8. The composition of a bone can be described in terms of the mineral phase hydroxyapatite the organic phase which consists of collagen type I noncollagenous proteins other components and water. Collagen is the main fibrous protein in the body.

The relative proportions of these various components vary with age site gender disease and treatment. Essentially collogen fibers makes the bone somewhat flexable Inorganic Portion of Bone -compose about 65 of the mass of the bone -hydroxyapatites or mineral salts calcium phosphates -provides the incredible hardness of bones to resist compression forces Spina bifida. The remaining material is mostly collagen with trace amounts of.

The elasticity of collagen improves fracture resistance. These salt crystals form when calcium phosphate and calcium carbonate combine to create hydroxyapatite. Chemical Composition of Bone Bone is made up of both organic and inorganic components.

What is the Composition of bone. It is composed predominantly of collagens non-collagenous glycoproteins hyaluronan and proteoglycans. The composition of a bone is spongy bone narrow compact yellow bonefat storage osteoblasts cell bone marrow by kaitlyn sears tropocollagen collagen Calcium.

Composition of bone Bone itself consists mainly of collagen fibres and an inorganic bone mineral in the form of small crystals University of Cambridge 2005. Bones are living tissue which is made up of connective tissue.

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